
Anti-ARRB2 Polyclonal Antibody
产品名称: Anti-ARRB2 Polyclonal Antibody
英文名称: Anti-ARRB2 Polyclonal Antibody
产品编号: K002346P
产品价格: null
产品产地: 北京
品牌商标: solarbio
更新时间: 2025-03-04T13:05:03
使用范围: WB
北京索莱宝科技有限公司
- 联系人 : 索莱宝-龚思雨
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Anti-ARRB2 Polyclonal Antibody
品牌:solarbio | 货号:K002346P
英文名称 | Anti-ARRB2 Polyclonal Antibody |
---|---|
别名 | ARB2;ARR2;BARR2 |
应用 | WB |
稀释比例 | WB 1:500-2000. |
交叉反应 | Human |
蛋白分子量 | 46kDa |
Gene ID | 409 |
保存 | Store at -20°C. Avoid freeze / thaw cycles. |
储存液 | Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
纯化方法 | Affinity purification |
亚型 | IgG |
免疫原 | A synthetic Peptide of human ARRB2 |
性状 | 液体 |
Public Immunogen Range | A synthetic Peptide of human ARRB2 |
Subcellular Locations | Cell membrane Cytoplasm Cytoplasmic vesicle Membrane Nucleus clathrin-coated pit |
Swiss Prot | P32121 |
克隆类型 | Polyclonal Antibody |
背景资料 | Members of arrestin/beta-arrestin protein family are thought to participate in agonist-mediated desensitization of G-protein-coupled receptors and cause specific dampening of cellular responses to stimuli such as hormones, neurotransmitters, or sensory signals. Arrestin beta 2, like arrestin beta 1, was shown to inhibit beta-adrenergic receptor function in vitro. It is expressed at high levels in the central nervous system and may play a role in the regulation of synaptic receptors. Besides the brain, a cDNA for arrestin beta 2 was isolated from thyroid gland, and thus it may also be involved in hormone-specific desensitization of TSH receptors. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene. |